Changes in hepatic cyclic nucleotides levels in CCl4-treated rats
نویسندگان
چکیده
منابع مشابه
Effect of Primidone on Liver Enzymes Levels and Hepatic Tissue Changes in Adult Male Rats
Background: Primidone is effective in the treatment of epilepsy. In this research, effect of primidone on levels of liver enzymes and liver tissue change in adult male rats was studied. Material and Methods: For this purpose, 40 adult male wistar rats, weighing approximately 180-200 g were divided into 5 groups of 8 animals. Groups: control group, Sham group and treatment at doses of 20, 40, 60...
متن کاملPrevention of fibrosis progression in CCl4-treated rats: role of the hepatic endocannabinoid and apelin systems.
Endocannabinoids behave as antifibrogenic agents by interacting with cannabinoid CB2 receptors, whereas the apelin (AP) system acts as a proangiogenic and profibrogenic mediator in the liver. This study assessed the effect of long-term stimulation of CB2 receptors or AP receptor (APJ) blockade on fibrosis progression in rats under a non-discontinued fibrosis induction program. The study was per...
متن کاملHepatoprotective Activity of Cucumis trigonus Roxb. Fruit Against CCl4 Induced Hepatic Damage in Rats
In India, a number of medicinal plants and their formulations are used to cure hepatic disorders in traditional systems of medicine. No systemic study has been done on protective effect of Cucumis trigonus Roxb. (Cucurbitaceae) to treat hepatic diseases. Protective action of C. trigonus fruit extracts was evaluated in this study in animal model of hepatotoxicity, which was induced by carbon tet...
متن کاملHepatoprotective Activity of Cucumis trigonus Roxb. Fruit Against CCl4 Induced Hepatic Damage in Rats
In India, a number of medicinal plants and their formulations are used to cure hepatic disorders in traditional systems of medicine. No systemic study has been done on protective effect of Cucumis trigonus Roxb. (Cucurbitaceae) to treat hepatic diseases. Protective action of C. trigonus fruit extracts was evaluated in this study in animal model of hepatotoxicity, which was induced by carbon tet...
متن کاملChanges in Catecholamines and Acetylcholinesterase Levels of Crebellum, Mid-brain and Brain Cortex in Chromium Treated Rats
The short and long term effects of chromium toxicity on brain catecholamines and acetylcholinesterase levels were investigated. Rats were injected daily with varying amounts of chromium. The short term (2 h) administration of chromium (8 mmol/kg) reduced catecholamines level of cerebellum, mid-brain and brain-cortex by 22.8, 19.4 and 21.2% respectively. Acetylcholinesterase activity was also re...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 1982
ISSN: 0021-5198
DOI: 10.1016/s0021-5198(19)54093-8